Associations between Small Dense LDL, HDL Subfractions (HDL2, HDL3) and Risk of Atherosclerosis in Japanese-Americans
نویسندگان
چکیده
منابع مشابه
Associations between small dense LDL, HDL subfractions (HDL2, HDL3) and risk of atherosclerosis in Japanese-Americans.
AIM Small dense low-density lipoprotein (sdLDL) has been suggested to be more atherogenic than large buoyant LDL. High-density lipoprotein (HDL) consists of two major subfractions (HDL2, HDL3), and just as controversy remains regarding which of the two is the more powerful negative risk factor for atherosclerosis, associations between sdLDL and these HDL subfractions are unclear. METHODS We m...
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BACKGROUND We investigated the association of cholesterol concentrations in serum high density lipoprotein (HDL) and its subfractions HDL2 and HDL3 with the risk of acute myocardial infarction in 1,799 randomly selected men 42, 48, 54, or 60 years old. METHODS AND RESULTS Baseline examinations in the Kuopio Ischaemic Heart Disease Risk Factor Study were done during 1984-1987. In Cox multivari...
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The major Lipoprotein classes are heterogenous. Human serum High-Density-Lipoproteins (HDL) are separated into two major subfractions (HDL2, d=1.063-1.125 g/ml, HDL3, d=1.125-1.210 g/ml) by a simple double precipitation method. There was a strong inverse relation between HDL-Cholesterol (HDL-C) and subfractions HDL2-C and HDL3-C with atherosclerosis. This study demonstrated that HDL-C (P<0.001)...
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Carotid Lipid Core Measured by MRI To the Editor: A strong relationship exists between cholesterol and atherosclerosis,1 with low density lipoprotein (LDL) being a major risk factor.2 However, 50% of patients with acute coronary events have “normal” cholesterol, and 75% patients with premature coronary heart disease (CHD) have normal LDL.3 Thus, contribution of other lipoproteins has been explo...
متن کاملFatty liver is independently associated with alterations in circulating HDL2 and HDL3 subfractions.
F atty liver is associated with insulin resistance, atherosclerosis, and the metabolic syndrome (1–7) and predicts future cardiovascular events (4–8). The pro-atherogenic serum lipid profile in subjects with fatty liver is characterized by elevated levels of triglycerides, low HDL cholesterol, and an increase in small dense LDL particles (9–12). Regarding HDL, not only quantitative, but also qu...
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ژورنال
عنوان ژورنال: Journal of Atherosclerosis and Thrombosis
سال: 2012
ISSN: 1340-3478,1880-3873
DOI: 10.5551/jat.11445